Before propensity score weighting, the laparoscopic group had a greater proportion of patients with higher BMI, less previous colorectal surgery, comorbidity of hypertension, preoperative carcinoembryonic antigen < 5 ng/mL, serum albumin level > 3.5 mg/dL, early tumor stage, well-differentiated histologic grade, retrieved lymph node > 12, and smaller tumor size compared with the open group. The gene discussed is ALB; the disease is hypertensive disorder.