CD27 and classic Hodgkin lymphoma: Conversely, the proportion of CD27+IgD− memory B-cells was lower in HIV-cHL cases than in controls (p = 0.005), while the frequencies of B-cells with a marginal zone-like phenotype (CD27+IgD+) did not differ significantly between HIV-cHL patients and controls (p = 0.62) (Table 2).