Factors related to unplanned hospitalizations were ECOG PS 2, IADL ≤ 7, ADL ≤ 5, Charlson Comorbidity Score ≥ 2, creatinine clearance ≤ 50 mL/min, albumin ≤ 35 g/dL, weight loss ≥ 5% and metastatic disease. Here, ALB is linked to metastatic neoplasm.