CD274 and neoplasm: In order to investigate on the effects of anti-PD-L1 or anti-LAG-3 mAbs on HuT-78 in the presence of lymphocytes, we co-cultured tumor cells with hPBMCs (Effector:Target cells ratio 5:1) for 48 h and treated them with atezolizumab, PD-L1_1, LAG-3_1, or their combinations.