In support of these findings, in a cohort study (NHS and HPFS), higher adherence to dietary pattern scores which reflect the dietary inflammatory potential (predictive of inflammatory biomarkers) and patterns related with insulin resistance/hyperinsulinemia (predictive of C-peptide as an indicator of insulin secretion and the triglyceride to high-density lipid-cholesterol ratio as an indicator of insulin resistance), were related with higher risks of developing HCC [8]. The gene discussed is INS; the disease is hepatocellular carcinoma.