AKT1 and Familial prostate cancer: The inhibition of p-AKT by NFV was reported in other cancers, such as breast cancer [72,73], multiple myeloma [15,74], acute myeloid leukemia [75], pediatric refractory leukemia [76], diffuse B-cell lymphoma [77], prostate cancer [78], and non-small cell lung carcinoma [79].