For example, CTNNB1 is the gene encoding for β-catenin and the deregulation of the WNT/CTNNB1 (β-catenin) pathway is a well-established event in the carcinogenic process in several neoplasias, including colorectal cancer [172,173,174], hepatocellular carcinoma [175,176,177] and cutaneous melanoma [178,179,180], among others. Here, CTNNB1 is linked to hepatocellular carcinoma.