Data presented by Wang and colleagues showed that dexamethasone suppresses the growth of NSCLC cell line A549 injected xenograft tumors via inducing estrogen sulfotransferases and decreasing estradiol levels in tumor tissues, suggesting that dexamethasone may be used as an anti-estrogenic agent for the NSCLC treatment [138]. This evidence concerns the gene SULT1E1 and non-small cell lung carcinoma.