Cytokines and chemokines implicated in inflammation control (IL-6, IL-4, IL-10) and immune recruitment (IL-5, IL-15, LIF, CX3CL1, IFN-γ...) were analysed in the tumour microenvironment, contralateral mammary gland, inguinal adipose tissue and gastrocnemius, and were related to immune checkpoint (PDL-1, PDL-2) and cytotoxic effectors (granzyme A and perforin 1). The gene discussed is IL4; the disease is neoplasm.