AUCs were lower for triple-negative (N = 132, AUC range 0.564–0.585) and HER2+ cancers (N = 224, AUC range 0.513–0.567) compared with ER/PR+HER2− cancers (N = 1316, AUC range 0.605–0.629). This evidence concerns the gene ESR1 and cancer.