The combination of SLC26A9 with AP002478.1, BHLHA15, FFAR2, IGFBP1, KCTD8, and PHYHD1 was also identified as a gene signature for personalized prognosis prediction and targeted therapy of esophageal adenocarcinoma [41]. The gene discussed is IGFBP1; the disease is esophageal adenocarcinoma.