AKT1 and cancer: Taking into consideration that after activation of Akt/mTOR signaling, the cachectic muscles preserves their growth ability, which seems to be due to a better function in the eukaryotic initiation factors, and that up to now no pharmacological agent against chronic disease-related muscle wasting has been identified, future studies should investigate whether and how recently described muscle-specific chemical compounds [51,56] could be possible alternatives to counteract cancer cachexia.