BCL6 inhibits the expression of p53 and regulates the DNA damage-induced apoptotic responses in GC B-cells [22,23,24]; thus, we also studied the link between TP53 mutations and RNA expressions of BCL6 and BACH2, which showed no correlation, implying TP53-independent functions for these regulators in CLL (Table S3A,B). The gene discussed is TP53; the disease is B-cell chronic lymphocytic leukemia.