PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, Delta Isoform), an oncogene that is commonly found to be overexpressed or amplified in p53WT cancers, including breast and ovary [16,17,18], encodes the protein wild-type, p53-induced phosphatase 1 (WIP1), which is a direct transcriptional target of p53. The gene discussed is PPM1D; the disease is cancer.