A few innovative targeted therapies are now available for ovarian cancer, including the anti-angiogenetic antibody bevacizumab [3] and the PARP inhibitors olaparib, rucaparib and niraparib, which are FDA-approved as maintenance treatments for platinum-sensitive recurrent ovarian cancer patients harboring a germline or somatic BRCA1/2 mutation (in the case of olaparib) while independent of BRCA status in the cases of rucaparib and niraparib [9,10,11,12,13]. The gene discussed is BRCA1; the disease is ovarian cancer.