A previous study has reported that expression of circHIAT1 is downregulated by AR in cancer cell lines and tumor tissue of clear cell renal cell carcinoma (ccRCC) cancer, and this led to increased proliferation, migration, and invasion of tumor cells in vitro and in vivo, as well as poor clinical features, including a worse overall survival of the patients.14 The gene discussed is AR; the disease is nonpapillary renal cell carcinoma.