YAP1 and myocardial infarction: Similarly, in vivo, both activation of YAP and deletion of Salv drove the expression of cell cycle proliferation-related genes and improved cardiac function and survival after MI/iHF (ischemic HF) in adult mice, specifically manifested as the increase of cardiomyocyte proliferation, the recovery of pumping function, the weakening of fibrosis, and the enhancement of contractility [129, 134, 135].