Likewise, the miR-27a/ZBTB10/Sp/EGFR axis was also observed in colon cancer cells after treatment with ethyl 2-((2,3-bis(nitrooxy)propyl)disulfanyl)benzoate (GT-094, a novel nitric oxide chimera that induces ROS production) [61]. This evidence concerns the gene TFF2 and malignant colon neoplasm.