C3 and myositis disease: Serum CK was 3008 U/L and serology showed ANA 1/1280–1/2560 (mixed homogeneous and nucleolar pattern), with positive anti-PM/Scl 75 and anti-PM/Scl-100, dsDNA 71 (Crithidia negative), positive SSA and borderline SSB and negative myositis-specific antibodies. There was a polyclonal hyper-gammaglobulinemia, IgG 28.1 g/L, low C3 (0.7) and C4 (0.13), and 25OH vitamin D was deplete, 18 nmol/L.