A common side effect of statins is myopathy, and this complication can be exacerbated by the concomitant use of some other drugs, especially those that inhibit CYP3A4 as the cytoplasmic enzyme responsible for the metabolization of statins such as simvastatin, lovastatin, and atorvastatin [10]. The gene discussed is CYP3A4; the disease is myopathy.