Previously, it was thought that Th1-cells are the major pathogenic cells in MS since these cells and Th1-like cytokines (such as interferon-γ (IFN-γ) and IL-2), are abundantly present in spinal cord and brain lesions of experimental autoimmune encephalomyelitis (EAE) animals, an animal model that mimics MS [19]. Here, IFNG is linked to myeloid sarcoma.