Among that, Lrp5 [20], Cyp7a1 [21], Nfkbiz [22], Sigmar1 [23], Fabp7 [24], and Hao1 [25] (Figure S1) have been reported in the inflammatory response and lipid metabolic process, suggesting that these genes may play an important role in modulating sepsis-induced system inflammation in WT and LBP-deficient rats after LPS injection. The gene discussed is HAO1; the disease is Sepsis.