Regarding IL-6 and IL-10, these cytokines have been associated with high clinical disease activity in SLE, while IL-13 induces the expression of IgE, IL-6, and surface antigen such as CD23, CD71, and MHC II, which together could contribute to the exacerbation of the disease [5]. The gene discussed is FCER2; the disease is systemic lupus erythematosus.