FGF21 and metabolic dysfunction-associated steatotic liver disease: In all, molecular mediators linking NAFLD with diabetic retinopathy might include an increased release of some pathogenic mediators from the liver, such as FGF21 (Fu et al., 2017), HGF (Nakabayashi et al., 2003), C-reaction protein, reactive oxygen species, IL-6 and TNF-α (Targher et al., 2008), which in turn determine the disease progression, forming eye-liver communication.