Firstly, GSEA was performed to probe the latent functional enrichment pathways of the TME-related lncRNAs signature, and the results revealed that tumor-related pathways, including bladder cancer, renal cell carcinoma, DNA replication, cell cycle, ErbB, and Notch signaling pathway, were highly enriched in the high-risk group (p < 0.05; Figure 8A). This evidence concerns the gene EGFR and hereditary clear cell renal cell carcinoma.