MAP3K8 and neoplasm: The enhanced expression and activity of MAP3K8 were associated with poor prognosis and implicated in tumor progression such as cell proliferation, migration, invasion, stemness, angiogenesis, epithelial-to-mesenchymal transition, and metastasis (Vougioukalaki et al., 2011; Gantke et al., 2012; Gruosso et al., 2015).