SDC2 and adenoma: Ct values of the tissue samples (Figure 2A) showed a highly significant difference (p < 0.001) between CRC and the control for either SDC2 or TFPI2. Ct values of the stool samples showed highly significant differences in SDC2 and TFPI2 between CRC, adenoma, and control (Figure 2C), with a similar tendency of normal > adenoma > CRC.