YTH n6-methyladenosine RNA binding protein 2 (YTHDF2) is downstream of epidermal growth factor receptor/src proto-oncogene, non-receptor tyrosine kinase/extracellular signal-regulated kinase (EGFR/SRC/ERK) and plays an important role in the proliferation and invasion of glioma cells. Here, YTHDF2 is linked to central nervous system cancer.