KAT2A and neoplasm: α-KGDC binds to the promoter regions of lysine acetyltransferase 2A (KAT2A, also known as GCN5), and KAT2A also acts as a succinyltransferase and succinylates histone H3 on lysine 79, which facilitates histone succinylation and tumor cell proliferation (Wang et al., 2017).