NRIP2 and focal segmental glomerulosclerosis: To determine whether our findings have clinical relevance, we examined NRIP2 expression in human kidneys using the Nephroseq database (http://www.nephroseq.org) (Ju et al., 2015), which showed (Figure 6A) that glomerular expression of NRIP2 was induced in kidneys from human patients with minimal change disease (MCD), FSGS and membranous nephropathy (MN) but not in kidneys from those with IgA nephropathy (IgAN).