IGF2BP1 and cancer: In breast cancer, a recent study showed that lncRNA KB-1980E6.3 can augment cancer cell self-renewal and maintain the stemness of cancer cells under a hypoxic microenvironment, indicating that targeting the lncRNA KB-1980E6.3/IGF2BP1/c-Myc axis may be a promising therapy for refractory hypoxic tumours (Zhu et al., 2021).