In NSCLC, the METTL3/YTHDF3 complex enhances the stability of lncRNA MALAT1, regulating the MALAT1-miR-1914-3p-YAP axis to increase YAP expression and induce drug resistance (Jin et al., 2019); METTL3, as a direct target gene of miR-4443 in tumour exosomes, is involved in regulating FSP1 expression and interferes with the ferroptosis induced by cisplatin, resulting in drug resistance (Song et al., 2021). Here, YAP1 is linked to non-small cell lung carcinoma.