Definitely patients with PD-L1>50% and KRAS-mutant NSCLC had favorable survival (mOS ≥20 months) with either ICI monotherapy or chemoimmunotherapy, while patients with KRAS wild type who were treated with ICI monotherapy had worse survival compared with those treated with chemoimmunotherapy (39). The gene discussed is CD274; the disease is non-small cell lung carcinoma.