DNMT1 and cancer: Multiple recent studies have highlighted diverse miR-148b-3p target genes in a range of human tumor types (24–28), with some prior evidence demonstrating that this miRNA can directly target oncogenes including DNMT3b (25), CCK2R (26), DNMT1 (28), CEA (29), and AMPKα1 (30) in various cancers, thereby functioning as a tumor suppressor.