For example, two cohorts (GSE4475 and GSE5122) included 158 B-cell lymphoma samples and 58 AML samples revealed that PTPRO upregulation was related to poorer prognosis (OS HR = 2.02, 95% CI = 1.46 to 2.18, Cox P = 0.00002; OS HR = 1.62, 95% CI=1.12 to 2.34, Cox P = 0.01). Here, PTPRO is linked to acute myeloid leukemia.