Stable low expression of ANXA2 ovarian cancer cells OV-shA2-1/OV-shA2-2 and ES-shA2-1/ES-shA2-2 and their negative control groups OV-NC and ES-NC were constructed by lentivirus, the results showed that after inhibition of ANXA2 expression, there was no significant change in the expression of CD147 protein (Supplementary Figure 3B). The gene discussed is BSG; the disease is ovarian cancer.