The ZNF750 mRNA expression was significantly increased 4505.9-folds and 55.8-folds in the CAL-27oeZNF750 cells and xenograft tumor samples respectively, while knockdown of the ZNF750 gene leaded to 77.8% and 60% down-regulation of ZNF750 in the CAL-27shZNF750 cells and xenografts tumor samples. The gene discussed is ZNF750; the disease is neoplasm.