Prognostic analysis using the TCGA database to explore the impact of core genes on the prognosis of BLCA found that survival analysis of noninvasive urothelial carcinoma showed that 18 targets are associated with prognostic survival as shown in Figure 7; the overall survival of patients with high gene expression and those with lower than low expression include ADRA1D, ADRA1A, CALM1, CHRM2, COL3A1, CYP1B1, DPP4, GJA1, JUN, MAOB, PGR, PTGER3, PTGS1, RUNX1T1, and SLC2A4. The gene discussed is GJA1; the disease is bladder transitional cell carcinoma.