Kaempferol is a flavonoid that suppresses bladder cancer cell development via the c-Met/p38 signaling pathway, hence preventing bladder cancer development, invasion, and metastasis [24].Quercetin, is a flavonoid, a kind of polyphenolic substance that suppresses bladder cancer cell proliferation, cell proliferation, and hypermethylation. This evidence concerns the gene MET and urinary bladder carcinoma.