The renin activity in patients with ARA of the diagnosed hypertension group (2.19 ± 2.91) was higher compared to patients with ARA of undiagnosed hypertension group (1.43 ± 2.07) and also higher than patients with NAR of diagnosed hypertension group (1.75 ± 2.85) (p < 0.001, both). The gene discussed is REN; the disease is hypertensive disorder.