In CRC, there is mounting evidence indicating there are crosstalks between miRNAs and the Wnt/β-catenin signaling pathway [63], EGFR signaling pathways [64], TGF-β signaling pathway [65], TP53 signaling pathway [66], and the EMT [67] in progression and metastasis. This evidence concerns the gene TGFB1 and colorectal carcinoma.