CD79A and neoplasm: Accumulating evidence has shown the critical role of intestinal barrier function regulated by mucus, IgA, and lipocalin2 in protecting from bacteria-induced inflammation and tumor tumorigenesis, and numerous signaling pathways (e.g., Toll-like receptors), metabolites (e.g., indole, bile acids), and small non-coding RNAs (e.g., miRNA, piRNA) have been identified as key regulators mediating interactions between host and microbe in the intestine [57].