DDX39B and cancer: DDX39B is involved in the regulation of pre-mRNA splicing, nuclear export of mRNAs, and pre-ribosomal RNA translation, and may promote the genesis, development, and metastasis of multiple cancer types by regulating cell proliferation (Awasthi et al., 2018; Gu et al., 2020; Xu et al., 2020; He et al., 2021).