However, it could be also induced to express in tumor cells and intratumoral cells, including DCs, macrophage, endothelial cells, cancer-associated fibroblasts (CAFs), and mesenchymal stem cells (MSCs) (28–34), by a variety of inflammatory stimuli, such as interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), IL-32, and IL-6 (33, 35–37). Here, TNF is linked to neoplasm.