Another study showed that the levels of a set of lncRNAs, HOTAIR, Luca-15 Specific Transcript (LUST), anti-NOS2A, MEG, TUG1, NEAT1, Small Nucleolar RNA Host Gene 4 (SNHG4), Highly Accelerated Region 1B (HAR1B), and GAS5, have higher expression levels in seral exosomes of patients with RA (n=28) than in the seral exosomes of normal controls (n=10) (89). The gene discussed is HAR1B; the disease is rheumatoid arthritis.