Since miRNAs from the miR-30 family target critical components of the calcium/CaN signaling pathway in podocytes, including TRPC6, PPP3CA, PPP3CB, PPP3R1 and NFATC3 (28), dysregulated miR-30 expression might be essential for aberrant T cell-mediated immune responses in GCA arterial lesions. This evidence concerns the gene NFATC3 and temporal arteritis.