Further, Akt expression was highly increased in HMEC-HCMV-DB (p-value(HCMV-DB: HMEC-UI) = 0.03), compared to HMEC-HCMV-TB40/E at day 3 post-infection (p-value(HCMV-TB40/E: HMEC-UI) = 0.06), and an increase in its phosphorylation on both serine 473 and threonine 308 in HMEC-HCMV-DB was observed (Figures 6A, D). The gene discussed is AKT1; the disease is infection.