The heatmap of immune cell infiltration (based on CIBERSORT, MCP-counter, xCell, EPIC, TIMER, quanTIseq and IPS algorithms) indicated that the low-m6Ascore group had higher immune cell infiltration, especially regarding anti-tumor-related cells (CD8+ T, dendritic, natural killer, and Th1 cells) (Figure 4B). This evidence concerns the gene CD8A and neoplasm.