TNF and Behcet disease: The general trend was that patients on neither COLC or AZA had slightly higher IL-1β, IL-2, IL-4, IL-5, IL-6, IL-12p70, IL-17A, IFN-γ, TNF-α and β saliva concentrations than BD patients on both AZA and COLC treatment however this was not significant (Table 4B).