In addition to CD4+ Th17 cells, IL-17A is produced by γδ T cells, NK cells (120), and is secreted by CD3+ (CD4-/CD8-) cells infiltrating salivary glands in Sjögrens syndrome (121) and in the plasma from those with systemic lupus erythematosus (122). The gene discussed is CD8A; the disease is systemic lupus erythematosus.