IL-8 levels were higher in saliva than serum with the group median levels of salivary IL-8 in BD (MA and MQ) and RAS (MA and MQ: data not shown, RAS-ALL Supplementary Table S2) all higher than HCs however in serum, only BD IL-8 levels were higher (Table 3). The gene discussed is CXCL8; the disease is acute lymphoblastic leukemia.