As compared to the NAFLD group, 5-HT2cR, 5-HT2bR, Leptin, AGRP, NPY, and CRF expression decreased in the hypothalamus and stomach of the 919TJ group, while Ghrelin and GHSR expression increased in both sites (*P < 0.05, **P < 0.01, ***P < 0.001). The gene discussed is LEP; the disease is metabolic dysfunction-associated steatotic liver disease.