As shown in Table 2, univariate Cox analysis of the development cohort revealed that advanced age, pulse pressure, WBC, NT-proBNP, ΔScr, AKI stage, serum kalium levels, 25(OH)D3, heart failure, and MODS were related factors for all-cause death of diabetic patients with AKI (p < 0.05). This evidence concerns the gene NPPB and acute kidney injury.