There was no significant difference in sex, age, diabetes duration, BMI, blood pressure, white blood cell count (WBC), platelets, hemoglobin, 25(OH)D3, creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), NT-proBNP, FBG, PBG, glycosylated hemoglobin A1c (HbA1c), blood urea nitrogen (BUN), baseline Scr, uric acid (UA), serum kalium levels, incidence of RRT, heart failure, CKD, bacterial infections, or MODS (p > 0.05). This evidence concerns the gene NPPB and diabetes mellitus.