It was used to investigate a transgenic zebrafish model of inherited long QT syndrome in which a loss of rapid delayed-rectifier potassium current (IKr) due to a mutation in the s290 allele of the kcnh2 gene (kcnh2s290) results in mechanical ventricular asystole (Arnaout et al., 2007). The gene discussed is KCNH2; the disease is Prolonged QT interval.