Examining these relationships with respect to pain triggers, in individuals with photophobia, oral α2δ ligands (OR = 2.18, 95%CI 1.78–2.21, p = 0.05) and muscle relaxants (OR = 1.32, 95%CI 1.31–1.34, p < 0.005) remained in the model, while in individuals with cutaneous allodynia, oral α2δ ligands (OR = 1.79, 95%CI 1.76–1.80, p < 0.005) and topical cyclosporine/lifitegrast (OR = 1.13, 95%CI 1.11–1.18, p < 0.005) remained in the model. The gene discussed is ATXN2L; the disease is Photophobia.