AMF increases the autophagic flux of glioma U251 and U373 cells via up-regulating the autophagy-relevant proteins, such as Beclin1, LC3B, ATG5, ATG7 (Chen et al., 2020c) and the phosphorylation of AMPK or suppressing the phosphorylation of mTOR and p70S6K (Chen et al., 2020c). Here, ATG7 is linked to central nervous system cancer.